CMEonHIV.com is dedicated to providing online CME presentations (slides with voiceover) on HIV/AIDS for healthcare professionals given by local and international experts to keep you up-to-date on the ongoing developments in the field.
Conference
"Is it Superior to be Non-inferior? - HIV Statistics made Simple" Naomi Givens (biography) English - 2005-02-18 - 41 minutes
(53 slides)
Summary : Time to brush up on your statistics! Naomi Givens, a statistician with GlaxoSmithKline, reviews the different study designs commonly used in HIV trials. Why is one design chosen over another? What is the difference between the frequently analyzed HIV treatment endpoints and how are they calculated? And just how are the P-value and the confidence interval different?
All of these questions and more are answered in this concise review that is sure to increase your stats savvy.
Also, be sure not to miss an explanation of the Context Study results.
Learning objectives : After viewing this presentation, participants will be able to discuss:
• The difference between a superiority design and a non-inferiority design
• The reasons why one would choose one design over the other
• How to interpret confidence intervals in both superiority and non-inferiority studies
• The relationship of the P-value to the confidence interval
• How end-points in HIV studies are calculated and what they tell us
• The results of the CONTEXT study
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