CMEonHIV.com is dedicated to providing online CME presentations (slides with voiceover) on HIV/AIDS for healthcare professionals given by local and international experts to keep you up-to-date on the ongoing developments in the field.
Conference
"Trends in HIV Drug Resistance Testing" Pr. Richard Harrigan (biography) English - 2002-04-14 - 40 minutes
Summary : HIV drug resistance testing using genotyping methods are now well established in clinical practice. However, the large number of potential combination therapies, and the vast number of permutations drug resistance mutations means that there is still relatively little data based evidence linking any particular genotype with clinical outcomes. Furthermore, the confounding effects of incomplete adherence, cross-resistance, and the reversion of mutations upon stopping or changing therapies mean that interpretation of this data will be difficult even with large treatment response databases. I will summarize the contribution of these factors to observed HIV drug resistance in the British Columbia cohort, and suggest a potential alternative analytical approach. Finally, I will summarize trends observed in the HIV drug resistance program in samples from 1996-2001.
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